Past Projects
DNA translesion synthesis inhibition
Circumventing platinum-based anti-cancer drug resistance.
Biomarkers of cancer drug-responses
Quantifying molecular markers, including DNA adducts, in biological samples to elucidate impacts on drug safety and efficacy.
Systems Toxicology
GutXen: Modeling the impact of gut microbial metabolism on food-born xenoestrogen exposure
Evaluating the risk of endocrine-disruptive gastrointestinal metabolites by PBPK modeling and quantitative in vitro to in vivo extrapolation.
Sustainable Perfumes: Bridging Biocatalysis, Art and Consumer Behaviour.
Biocatalytic platforms for sustainable fragrance generation
Predicting liver injury from food-related chemical exposures
Establishing an integrated platform for predicting liver injury from food-related chemical exposures.
Urolithins: A bioinformatics / personalized nutrition approach to enlighten kinetics of beneficial gut microbial products. (UroKin)
Linking interindividual differences in the gut microbiome with pharmacokinetics of beneficial bacterial metabolites.
Tailoring DNA Scissors with Engineered High Specificity Glycosylase Enzymes
Generating novel glycosylases for diverse biotechnological applications via state-of-the-art protein engineering.